Supplementary Information -Time-course of coiling activity Version 1
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Time-course of coiling activity in zebrafish (Danio rerio) embryos exposed to ethanol as an endpoint for developmental neurotoxicity (DNT) – hidden potential and underestimated challenges
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Projects: Effect-Net, WP 9: Data management, aggregation and analysis, WP 1: Chemical analyses of test substances in water and biota and bioanalytics of stress response, WP 5: In vivo effects in model fish embryos and larvae, WP 7: Community-relevant effects, WP 8: Tool boxes for effect-based risk assessment, WP 2: Generation and characterization of metabolites, WP 3: In vitro effects 1: Receptor binding in non-cellular systems, WP 4: In vitro effects 2: Fish cells, WP 10: Mapping of the actors involved in the evaluation of biological hazards in aquatic ecosystems, WP 11: Actor perceptions and elaboration of guidelines and recommendations
Institutions: Universität Heidelberg
WP 1 first aims at identifying and quantifying relevant test substances from the groups of pharma-ceuticals (antidiabetics and neuroactive drugs such as selective serotonin reuptake inhibitors) and food additives (artificial sweeteners) in surface waters partly using existing expertise. The focus is on substances of high consumption and environmental relevance. Based on this analysis, the final test compounds will be defined (e.g. metformin, fluoxetine and sucralose), and specific methods for
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Abstract (Expand)
Authors: Florian Zindler, Franziska Beedgen, Thomas Braunbeck
Date Published: 21st Jun 2019
Journal: Chemosphere
